Debate analysis: Offhand I would say that Obama came off as looking more Presidential. Photo taken from here.

Update: another angle, taken from here.

US Republican presidential nominee Senator John McCain (R-AZ) reacts to almost heading the wrong way off the stage after shaking hands with Democratic presidential nominee Senator Barack Obama (D-IL) at the conclusion of the final presidential debate at Hofstra University in Hempstead, New York, October 15, 2008.
I would fault Senator McCain's debate coaches, as they obviously forgot to tell him not to stick his tongue out or drool.

Update 2: Jesus Christ! Here's another photo from the debate

U.S. Democratic presidential nominee Sen. Barack Obama (D-IL) (2nd R) and Republican presidential nominee Sen. John McCain (R-AZ) (2nd L) stand with their wives Cindy McCain (L) and Michelle Obama (R) after their presidential debate at Hofstra University in Hempstead, New York, October 15, 2008.

I love the way the caption ignores the most obvious thing about this photo. But in case you missed it, here's the closeup.

At least he didn't look at his watch.